In recent years, the abundance of hydro fluorocarbons (HFC) has been increasing, which has huge greenhouse potential value. It has an impact on global warming and also indirectly causes the destruction of the ozone layer. Scholars at home and abroad have carried out a wide range of in-situ ground measurements to obtain global abundance. At the same time, remote sensing technology can monitor the changes of HFC gas in a large range, for a long time and quickly, and has become an important means for the inversion of the gas concentration. The contents of in-situ measurement method, tracer ratio method, satellite inversion sensor development and satellite inversion method are described, and the advantages and disadvantages of different inversion methods are compared in combination with load characteristics analysis. Finally, discusses and prospects the existing problems and future development trend of current inversion.